Preterm Birth Impacts Over 1 in 10 U.S. Pregnancies1

Short & Long-term Health Consequences

Preterm birth is associated with health conditions that can impact babies at birth and throughout the rest of their lifetime. These issues affect not only the babies themselves, but also their families, employers, and payers.

Number 1

In the United States, prematurity has been estimated to account for one third of all infant deaths.2

Number 2

In the short term, premature babies often require special care through a NICU or special care nursery.

Number 3

Preterm infants are at increased risk of long-term health problems.3

Happy Couple With Hands On Pregnant Belly
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Preterm birth is a major driver of healthcare utilization and costs

The high cost of preterm births begins in the NICU, but often continues into later life. In 2016, the cost associated with prematurity in the United States was estimated at $25.2 billion. The per-child incremental lifetime costs for a preterm baby were 10 times higher than a full-term baby.4

Limitations of Traditional Preterm Birth Screening Methods

Identifying women at higher risk for preterm birth is a critical first step to addressing an early delivery’s health impacts. Up until this point, risk prediction tools have been limited, with only a small percentage of singleton pregnancies identified to be at risk for a spontaneous preterm birth.

Leveraging biomarkers from the blood for a comprehensive risk assessment

Advances in science now allow for earlier prediction, far greater accuracy, and the individualized insight to improve outcomes. The PreTRM® Test assesses protein biomarkers in the maternal serum to identify asymptomatic singleton pregnancies that are at higher risk for a premature birth. Greater than four times as many patients at higher can be identified using a comprehensive risk assessment comprised of the PreTRM Test and traditional screening methods than by using traditional methods alone.5

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Leveraging biomarkers from the blood for a comprehensive risk assessment

Advances in science now allow for earlier prediction, far greater accuracy, and the individualized insight to improve outcomes. The PreTRM® Test assesses protein biomarkers in the maternal serum to identify asymptomatic singleton pregnancies that are at higher risk for a premature delivery. In the PAPR study, greater than four times as many patients at higher risk were identified using a comprehensive risk assessment comprised of the PreTRM Test and traditional screening methods than by using traditional methods alone.5

Are you a payer or employer interested in the PreTRM® Test?

Contact us to learn more about the clinical and economic benefits of implementing a PreTRM Test & Treat strategy, which can be customized to your membership demographics and costs.

Contact Sera

References

  1. Hamilton BE, et al. Births: Provisional data for 2020. Vital Statistics Rapid Release; no 12. Hyattsville, MD: National Center for Health Statistics. May 2021.
  2. Callaghan WM, et al. The contribution of preterm birth to infant mortality rates in the United States. Pediatrics. 2006 Oct;118(4):1566-73.
  3. Boyle EM, et al. Effects of gestational age at birth on health outcomes at 3 and 5 years of age: population based cohort study. BMJ. 2012 Mar 1;344: e896.
  4. Waitzman NJ, et al. Preterm birth lifetime costs in the United States in 2016: An update. Semin Perinatol. 2021 Apr; 45(3):151390
  5. Saade GR, et al. Development and validation of a spontaneous preterm delivery predictor in asymptomatic women. Am J Obstet Gynecol. 2016;214(5):633.e1-24.
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